Immunität ohne Antikörper (Corona)

Annika, Luzern, Montag, 13.07.2020, 13:48 (vor 1384 Tagen) @ FourrierTrans
bearbeitet von Annika, Montag, 13.07.2020, 13:51

Eine Studie des Karolinska Instituts hat erst vor kurzem gezeigt, dass die Anzahl der Antikörper eher ein Marker für die Schwere der Coronaerkrankung ist, also besonders viele Antikörper bei besonders kranken Menschen gebildet werden. Die Immunität gegen das Virus, und somit ein milder, asymptomatischer Krankheitsverluaf, wird aber viel mehr durch T-Zellen vermittelt. Ebenfalls interessant ist, dass deutlich mehr Menschen T-Zellen-Immunität entwickelt haben, als "Antikörper-Immunität." und viele Menschen scheinbar eine Immunität gegen das Virus bilden, ohne dabei messbar nachweisbare Antikörper zu bilden.

https://news.ki.se/immunity-to-covid-19-is-probably-higher-than-tests-have-shown

"Our results indicate that roughly twice as many people have developed T-cell immunity compared with those who we can detect antibodies in.”

“One interesting observation was that it wasn’t just individuals with verified COVID-19 who showed T-cell immunity but also many of their exposed asymptomatic family members,” says Soo Aleman. “Moreover, roughly 30 per cent of the blood donors who’d given blood in May 2020 had COVID-19-specific T cells, a figure that’s much higher than previous antibody tests have shown.”

The T-cell response was consistent with measurements taken after vaccination with approved vaccines for other viruses. Patients with severe COVID-19 often developed a strong T-cell response and an antibody response; in those with milder symptoms it was not always possible to detect an antibody response, but despite this many still showed a marked T-cell response.

“Our results indicate that public immunity to COVID-19 is probably significantly higher than antibody tests have suggested,” says Professor Hans-Gustaf Ljunggren at the Center for Infectious Medicine, Karolinska Institutet, and co-senior author. “If this is the case, it is of course very good news from a public health perspective.